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. 2022 May 23;12:8626. doi: 10.1038/s41598-022-11612-y

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© The Author(s) 2022, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Single image quantification of the orientation of hASCs in response to a photografted pattern on day 13. (b and c) GFP-hASCs encapsulated at a density of 1000 cells per 1 µL in a gelatin-based hydrogel. Image was taken on day 13 after photografting. In image (b) the grafted structure is fluorescing in blue. This signal is suppressed in image (c) to highlight the cellular alignment. The scale bars represent 500 µm.