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. 2022 May 13;5:100157. doi: 10.1016/j.jtauto.2022.100157

Table 5.

RDW, NLR and PLR AUC-ROC analysis for active disease.

SLEDAI-2K ≥ 4
Hypocomplementemia
AUC-ROC Cut-off S 1-E AUC-ROC Cut-off S 1-E
RDW 0.561 13.93 0.46 0.24 0.646 13.21 0.74 0.40
NLR 0.630 1.97 0.69 0.40 0.639 1.68 0.74 0.38
PLR 0.680 154 0.77 0.47 0.644 127 0.85 0.56

AUC-ROC: Area Under the Curve - Receiver Operating Characteristic. S: Sensitivity, 1-E: Especificity, RDW: Red blood cell distribution width, PLR: Platelet-to-lymphocyte ratio, NLR: Neutrophil-to-lymphocyte ratio.

* The table shows the discrimination ability analysis of the three parameters by the AUC-ROC. The Youden index or cut-off point determines which will be the value with the best sensitivity (S) and specificity ratio (1-E) to predict active disease.