Table 6.
The combination effects of Nigrocin-PN with different antibiotics treated on several microbial strains
| Strains | Norfloxacin (lowest FICI) | Ampicillin (lowest FICI) | Vancomycin (lowest FICI) | Gentamicin (lowest FICI) c |
|---|---|---|---|---|
| S. aureus (NCTC 10,788) | 0.625 (NIa) | 0.375 (Sb) | 0.625 (NI) | 0.620 (NI) |
| MRSA (NCTC 12,493) | \c | \ | 1.125 (NI) | 0.500 (S) |
| E. coli (NCTC 10,418) | 0.625 (NI) | \ | \ | 0.750 (NI) |
| C. albicans (NYCY 1467) | 0.500 (S) | \ | 0.375 (S) | \ |
“NIa” represents “no interaction.”
“Sb” represents “synergy.”
“\c” represents “not studied.” Only the MICs of antibiotics fell between 64 and 0.125 µM were chosen to study the combination effect