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. 2022 May 10;13:900132. doi: 10.3389/fimmu.2022.900132

Figure 1.

Figure 1

Reduced endogenous melatonin levels caused metabolic disorders in EMR mice. (A) Serum melatonin level in Aanat−/− and wild-type (WT) mice (n =10). (B) Blood glucose level using the glucose tolerance test (GTT) (n = 7). (C) Blood glucose level using the insulin tolerance test (ITT) (n = 7). (D) Hematoxylin and eosin staining of the mouse brain (1000 μm), skin (50 μm), liver (50 μm), lungs (50 μm), and testis (50 μm) (n = 3-5). Differences between EMR and WT mice were assessed by Student’s t-test: *P < 0.05, **P < 0.01, ***P < 0.001.