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. 2022 May 10;13:808227. doi: 10.3389/fimmu.2022.808227

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Copyright © 2022 Depierreux, Kieckbusch, Shreeve, Hawkes, Marsh, Blelloch, Sharkey and Colucci

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Reduced arterial remodelling in females lacking MHC class I (A, B) Quantitative assessment of blood vessel size (A) and relative vessel wall thickness (B) at gd9.5 in mice of the indicated genotype (all mated with B6 males). Data representative of n=11-12 conceptuses from 4 litters each. (C) Qualitative assessment of disappearance of smooth muscle actin at gd9.5 by immunohistochemistry. Bars = 1mm (left panel), 250µm (right panel). Means ± SEM. P-values from unpaired two-tailed Student’s t-tests. See also Figure S3 .