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. 2022 May 10;13:890019. doi: 10.3389/fimmu.2022.890019

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Copyright © 2022 Li, Li, Wu, Xu, Teng, Yang, Sun, Zhao, Li, Liu, Yang, Gong and Cai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The specific phenotypes of LDLR+ MDSC. (A) Expression of differentially expressed genes in LDLR+ MDSC. (B) Flow cytometry analysis of MDSC fraction in normal and liver transplantation PBMC, and immunofluorescence including CD11b, CD14, and CD15 in normal and liver transplantation. (C) Enrichment analysis of Gene Ontology (GO) terms for differentially expressed genes in LDLR+ MDSC. (D) Fractions of LDLR+ MDSC in normal (n=3), stable (n=2), and rejection samples (n=2) after liver transplantation. Bulk RNA-seq expression of S100A8 and S100A9 in stable (n=129) and rejection samples (n=37) after liver transplantation. (E) Immunohistology of CD8, CD11b, CD14, and CD15 in liver transplantation tissue, and immunofluorescence including CD8, CD11b, CD14, and CD15 in liver transplantation.