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. 2022 May 23;12:8661. doi: 10.1038/s41598-022-12735-y

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© The Author(s) 2022, corrected publication 2022

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Effect of 5-fluorouracil and propolis administration on the expression of (A) TNF-α and (B) COX-2. Values are expressed as mean ± standard deviation (SD). Groups: Control, Normal saline; 5-FU, 5-FU 125 mg/kg; 5-FU + Pro, 5-FU 125 mg/kg + Propolis ethanolic extract 250 mg/kg/d; 5-FU + CLC, 5-FU 125 mg/kg + Colchicine 5 mg/kg/d. ^** indicate p < 0.01.