. 2022 May 23;12:8661. doi: 10.1038/s41598-022-12735-y

Table 2.

Electrocardiogram parameters of study groups.

Study groups	ECG parameters
Study groups	QRS interval (ms)	ST-segment (mV)	QTc (ms)
Control	12.38 ± 0.07	250.00 ± 22.21	115.60 ± 1.82
5-FU	14.82 ± 0.20****	457.80 ± 3.44****	142.60 ± 1.95****
5-FU + Pro	11.41 ± 0.18****^{, ####, $$$$}	217.20 ± 9.11**^{, ####, $}	114.20 ± 3.02^{####, $$$}
5-FU + CLC	12.11 ± 0.20^{####, $$$$}	241.70 ± 5.87^{####, $}	106.80 ± 3.11****^{, ####, $$$}

Values are expressed as mean ± standard deviation (SD). Groups: Control, Normal saline; 5-FU, 5-FU 125 mg/kg; 5-FU + Pro, 5-FU 125 mg/kg + Propolis ethanolic extract 250 mg/kg/d; 5-FU + CLC, 5-FU 125 mg/kg + Colchicine 5 mg/kg/d. **, and **** Indicate statistically significant difference compared to the control group (p < 0.01, and p < 0.0001, respectively). ^#### Indicate statistically significant difference compared to the 5-FU group (p < 0.0001). ^$, ^$$$, and ^$$$$ Indicate statistically significant difference between the treatment groups (p < 0.05, p < 0.001, and p < 0.0001, respectively).