Table 1.
Univariate and multivariate analysis of prognostic factors associated with OS and DFS in 167 HCC patients.
| HCC patients (n = 167) | Number | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|---|---|
| 5-year OS (%) | P value | HR (95% CI) | P value | 5-year DFS (%) | P value | HR (95% CI) | P value | ||
| Age(years): ≥55/<55 | 92/75 | 38.6/42.0 | 0.742 | 18.0/17.5 | 0.895 | ||||
| Sex: male/female | 137/30 | 41.5/28.4 | 0.097 | 18.8/15.0 | 0.201 | ||||
| HBV: Yes/No | 131/36 | 36.9/53.2 | 0.226 | 17.0/34.2 | 0.224 | ||||
| Liver cirrhosis: Yes/No | 90/77 | 41.5/38.6 | 0.741 | 17.0/18.9 | 0.322 | ||||
| Tumor size(cm): ≥3/<3 | 142/25 | 38.6/49.4 | 0.12 | 15.7/37.4 | 0.055 | ||||
| Mavi: Yes/No | 15/152 | 14.9/42.1 | 0.008 | 1.128 (0.482, 2.623) | 0.780 | 4.9/19.7 | 0.000 | 2.062 (0.904, 4.703) | 0.085 |
| Mivi: Yes/No | 93/74 | 29.3/49.4 | 0.025 | 1.495 (1.000, 2.235) | 0.050 | 12.0/21.2 | 0.101 | ||
| AFP(ng/ml): ≥20/<20 | 86/81 | 29.0/51.5 | 0.004 | 1.308 (0.933, 1.832) | 0.004 | 11.9/26.0 | 0.002 | 1.000 (1.000, 1.000) | 0.0001 |
| BCLC stage: 0&A/B&C | 141/26 | 46.7/15.9 | 0.001 | 1.963 (1.007, 3.825) | 0.048 | 19.8/6.538 | 0.000 | 1.535 (0.794, 2.965) | 0.202 |
| Staining score of DNAJC24: ≥1/<1 | 99/68 | 36.5/54.2 | 0.011 | 2.048 (1.352, 3.101) | 0.001 | 16.8/26.4 | 0.028 | 1.643 (1.129, 2.391) | 0.009 |
Bold is used to emphasize that the value is statistically significant.
AFP α-fetoprotein, BCLC Barcelona Clinic Liver Cancer, HBV, hepatitis B virus, Mavi macrovascular invasion, Mivi microvascular invasion.