Table I.
Ninety-five percent confidence intervals of sensitivity and specificities of common Lyme disease serology tests for stage 1 disease (adapted from Waddell et al).8
| Testing method | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|
| PCR (blood sample) | 33.8%-62.0% | NA |
| ELISA–pepC10 | 32.7%-44.0% | 97.7%-99.5% |
| ELISA–VlsE1 | 47%-77% | 98%-99% |
| ELISA–WCS | 60.9%-78.8% | 59.5%-83.5% |
| Western blot (Marblot/GenBio) | 42.7%-76.0% | 91.9%-98.7% |
CI, Confidence intervals; ELISA, enzyme-linked immunosorbent assay; NA, not applicable; PCR, polymerase chain reaction; WCS, whole-cell sonicate.