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. 2022 May 10;13:852945. doi: 10.3389/fphar.2022.852945

FIGURE 1.

FIGURE 1

48 h of high-glucose stimulation was the appropriate modelling condition. (A–C) The levels of AR mRNA, sorbitol and ROS in ARPE-19 cells under different high glucose stimulation duration. n = 3 per group. #p < 0.05, ##p < 0.01 vs. glucose dose 4.5 mM.