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Overview of the MHC molecules. (A) 3D structure of a pMHC-I complex (PDB ID: 1DUZ). The α chain is divided in IMGT defined domains by shades of light blue. The β-2 Microglobulin chain is shown in light orange. The peptide is shown in red. (B) 3D structure of a pMHC-II complex (PDB ID: 1AQD). The alpha chain is divided in IMGT defined domains by shades of light blue. The β chain is divided in IMGT defined domains by shades of orange. The peptide is shown in red.
