TABLE 1.
Basal parameters (i.e., pre-stress values) of mean arterial pressure (MAP), heart rate (HR), and tail skin temperature (T) after pharmacological treatment of either the anterior, rostral posterior, or caudal posterior regions of the insular cortex (IC) with the non-selective synaptic inhibitor CoCl2 or vehicle.
| Groups | n | MAP (mmHg) | HR (bpm) | T (°C) |
| Anterior IC | ||||
| Vehicle | 8 | 98 ± 1 | 370 ± 12 | 29.3 ± 0.4 |
| CoCl2 | 9 | 100 ± 2 | 344 ± 7 | 31.5 ± 0.6* |
| t = 1.2, df = 15 | t = 1.9, df = 15 | t = 2.9, df = 15 | ||
| P = 0.2373 | P = 0.0668 | P = 0.0096 | ||
| Rostral posterior IC | ||||
| Vehicle | 11 | 102 ± 2 | 351 ± 5 | 29.6 ± 0.6 |
| CoCl2 | 12 | 106 ± 2 | 355 ± 12 | 30.2 ± 0.5 |
| t = 1.2, df = 21 | t = 0.3, df = 21 | t = 0.8, df = 21 | ||
| P = 0.2439 | P = 0.7458 | P = 0.4481 | ||
| Caudal posterior IC | ||||
| Vehicle | 10 | 101 ± 2 | 354 ± 5 | 28.9 ± 0.1 |
| CoCl2 | 9 | 102 ± 3 | 378 ± 12 | 30.2 ± 0.4 |
| t = 0.4, df = 17 | t = 2.0, df = 17 | t = 0.9, df = 17 | ||
| P = 0.6942 | P = 0.0542 | P = 0.4559 |
Values are mean ± SEM, Student’s t-test.
*p < 0.05.