miR-141/200c deficiency leads to altered expression of genes in hepatic lipid metabolism in response to ethanol feeding. A–D, mRNA expression levels of genes were measured by qPCR in mouse livers and normalized to Rpl32 or Hprt (n=6–8). Data are presented as mean ± SEM. Statistical significance was assessed by Student’s t test; ∗p < 0.05, WT-CB versus WT-EB; ǂ, p < 0.05, WT-EB versus KO-EB. CB, LDC without ethanol supplementation plus maltose dextrin binge; EB, LDC supplemented with ethanol plus ethanol binge.