Table 3.
After vaccine 1st dose | After vaccine 2nd dose | |||
---|---|---|---|---|
Subjects with positive NAb, n (%) | Neutralizing activity (%) median (interquartile range) | Subjects with positive NAb, n (%) | Neutralizing activity (%) median (interquartile range) | |
PAPS, n=31 | 5 (16.1)a | 38.1 (32–55.5) | 24 (77.4) | 64.3 (49.0–77.0) |
Controls, n=108 | 38 (35.2) | 43.7 (34.2–66.4) | 85 (78.7) | 60.9 (45.6–81.3) |
p-Value (PAPS vs CG) | p =0.043 | p=0.275 | p=0.440 | p=0.689 |
Results are expressed in median (interquartile range) and n (%).
Nab—neutralizing antibodies; PAPS—primary antiphospholipid syndrome; CG—control group.
Positivity for Nab defined as a neutralizing activity ≥30% (cPass sVNT Kit, GenScript, Piscataway, USA).
ap <0.05 in comparison to controls.