TABLE 5.
Top genes identified for all cancer types. The genes are listed along with the number of samples they were labeled TSGs or OGs. Their presence or absence in CGC is also given.
| BRCA | COAD | LUAD | ||||||
|---|---|---|---|---|---|---|---|---|
| Gene | Samples | CGC | Gene | Samples | CGC | Gene | Samples | CGC |
| PIK3CA | 453 | Yes | APC | 408 | Yes | TP53 | 268 | Yes |
| TP53 | 383 | Yes | TP53 | 212 | Yes | KRAS | 186 | Yes |
| PRKCA | 239 | No | KRAS | 153 | Yes | STK11 | 135 | Yes |
| MYC | 235 | Yes | PIK3CA | 122 | Yes | CDKN2A | 133 | Yes |
| GATA3 | 230 | Yes | ARID1A | 87 | Yes | EGFR | 112 | Yes |
| PSMC5 | 229 | No | FBXW7 | 86 | Yes | KEAP1 | 111 | Yes |
| IKBKB | 228 | Yes | SOX9 | 81 | No | NF1 | 105 | Yes |
| PSMD12 | 228 | No | PRKDC | 73 | No | PSMD4 | 105 | No |
| MAP2K6 | 226 | No | SMAD4 | 72 | Yes | NFKBIA | 103 | No |
| RPS6KB1 | 225 | No | MTOR | 60 | Yes | MYC | 99 | Yes |