Table 3. Intervention Effects on Secondary Outcomes (Representing Components of Intervention and Additional Mobility Measures).
Outcome and time frame | Standard-plus | Standard | Adjusted difference (SE)a | P valuea | ||
---|---|---|---|---|---|---|
Mean (SD) | P value | Mean (SD | P value | |||
Lower extremity strength change, newtons | ||||||
12 wk | 7.5 (29.7) | .02 | 3.0 (23.6) | .21 | −1.8 (4.5) | .68 |
24 wk | −2.2 (35.5) | .60 | 2.0 (27.9) | .54 | −4.9 (4.6) | .30 |
36 wk | 5.7 (26.0) | .10 | −0.5 (24.8) | .89 | −4.0 (4.8) | .41 |
LE power change, watts | ||||||
12 wk | −14.3 (55.7) | .54 | −3.9 (61.4) | .02 | −11.0 (10.2) | .28 |
24 wk | −11.3 (49.5) | .06 | −6.0 (58.9) | .39 | −11.8 (10.1) | .24 |
36 wk | 0.6 (53.5) | .93 | −12.3 (68.7) | .17 | −13.0 (13.2) | .34 |
Six-minute walk distance change, m | ||||||
12 wk | 39.9 (63.4) | <.001 | 35.0 (53.5) | <.001 | 4.1 (9.0) | .65 |
24 wk | 31.8 (58.0) | <.001 | 20.6 (76.2) | .008 | 7.3 (10.2) | .47 |
36 wk | 34.5 (56.8) | <.001 | 26.1 (72.8) | <.001 | 9.9 (9.7) | .31 |
Figure of 8 time change, s | ||||||
12 wk | −1.0 (1.6) | <.001 | −1.0 (2.0) | <.001 | −0.1 (0.2) | .58 |
24 wk | −0.8 (1.5) | <.001 | −0.7 (2.2) | .002 | −0.1 (0.2) | .51 |
36 wk | −0.7 (1.6) | <.001 | −0.8 (2.2) | <.001 | −0.0 (0.2) | .98 |
Figure of 8 steps change, steps | ||||||
12 wk | −1.000 (2.3) | <.001 | −0.9 (2.3) | <.001 | −0.2 (0.3) | .56 |
24 wk | −1.0 (2.1) | <.001 | −0.4 (2.4) | .10 | −0.4 (0.3) | .19 |
36 wk | −0.7 (1.9) | <.001 | −0.7 (2.1) | .001 | 0.0 (0.3) | .95 |
Chair sit and reach change, cm | ||||||
12 wk | 0.6 (7.5) | .42 | 2.4 (7.2) | <.001 | −1.6 (1.0) | .12 |
24 wk | 1.8 (7.7) | .02 | 1.6 (8.4) | .06 | 0.8 (1.2) | .48 |
36 wk | −0.8 (7.9) | .34 | −0.1 (8.6) | .93 | −0.2 (1.2) | .87 |
Modified Gait Efficacy Scale change | ||||||
12 wk | −1.7 (10.8) | .09 | −0.2 (10.9) | .84 | −1.5 (1.3) | .28 |
24 wk | −1.4 (9.9) | .13 | −1.3 (9.5) | .13 | −0.3 (1.3) | .81 |
36 wk | −2.3 (12.0) | .046 | −1.6 (9.5) | .07 | −0.9 (1.3) | .49 |
Short Physical Performance Battery change | ||||||
12 wk | 0.2 (1.5) | .24 | 0.4 (1.3) | .002 | −0.2 (0.2) | .28 |
24 wk | 0.4 (1.4) | <.001 | 0.5 (1.3) | <.001 | −0.1 (0.2) | .68 |
36 wk | 0.2 (1.4) | .02 | 0.4 (1.3) | .002 | −0.2 (0.2) | .36 |
Obtained using a linear mixed model with multiple imputation for missing values.