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. 2022 May 11;4(3):fcac120. doi: 10.1093/braincomms/fcac120

Figure 6.

Figure 6

Sex-specific impact of Abca7 deletion on brain gangliosides. (A) A comparison of gangliosides in male Abca7 KO (n = 31) versus WT (n = 11) mice and distribution of gangliosides; t-test, *P < 0.05 t = 2.104. Each data point represents one animal. (B) A comparison of gangliosides in female Abca7 KO (n = 21) versus WT (n = 24) mice and distribution of gangliosides; t-test, *P < 0.05 t = 2.609. Each data point represents one animal. (C) Correlation between gangliosides and amyloid-β42 in male (n = 39) mice. (D) Correlation between gangliosides and amyloid-β42 in female (n = 44) mice.