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Fig. 4. Structural changes in the sexual stage of malaria. Efficacy of compound 1 (A) and 2 (B) against ookinete formation; (C) inhibition curve for both the compounds; (D) representative images of the DMSO control (healthy) ookinete and treatment with both the compounds at different concentrations. The photomicrograph of smears was stained with Giemsa shown at 1000× magnification.