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Antitumor activity of lanthomicins.
| Tumor cell lines | IC50 (μM/L) | |||
|---|---|---|---|---|
| Doxorubicin | Lanthomicin A | Lanthomicin B | Lanthomicin C | |
| A-549 (lung) | 0.02 | 0.17 | >100 | >100 |
| MCF-7 (breast) | 0.62 | 5.98 | >100 | >100 |
| HepG2 (liver) | 4.38 | 34.34 | >100 | >100 |
| HCT-116 (colon) | 10.58 | 82.27 | >100 | >100 |
