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. 2022 May 10;37(4):246–255. doi: 10.1089/cbr.2020.3587

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© Dandan Mao et al. 2022; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 3. — miR-944 was downregulated in IPA tissues and negatively regulated by SNHG6. (A) The expression of miR-944 in IPA tissues and NIPA tissues was detected by qRT-PCR. (B) The correlation between SNHG6 expression and miR-944 expression in IPA tissues was analyzed. (C) qRT-PCR was performed to detect the expression of miR-944 after SNHG6 was upregulated or downregulated in HP75 cells. (D) Schematic diagram of binding sites between wild-type or mutant-type SNHG6 and miR-944. (E) Dual luciferase reporter assay was used to validate the binding relationship between SNHG6 and miR-944. **p < 0.01; ***p < 0.001; p > 0.05. NIPA, noninvasive pituitary adenoma; n.s, no significance.