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. 2022 May 10;9:872457. doi: 10.3389/fnut.2022.872457

Table 2.

Clinical characteristics by NRS-2002 score.

Characteristics Overall (n = 289) NRS-2002 <3 (n = 156) NRS-2002 3–4 (n = 112) NRS-2002 ≥5 (n = 21) P-value
Female sex, n (%) 123 (42.6) 74 (47.4) 44 (39.2) 5 (23.8) <0.001
Age (year) 55.7 ± 17.3 53.4 ± 17.4b 55.9 ± 16.8 71.1 ± 9.2 <0.001
Age ≥70 y, n (%) 71 (24.6) 30 (19.2) 24 (21.4) 17 (81.0) <0.001
BMI (kg/m2) 24.0 ± 4.8 24.7 ± 5.0 23.3 ± 4.6 22.6 ± 4.2 <0.001
Comorbidities, n (%)
Coronary heart disease 6 (2.1) 3 (1.9) 1 (0.9) 2 (9.5) 0.038
Hypertension 91 (31.5) 43 (27.6) 38 (33.9) 10 (47.6) 0.138
Arrhythmia 15 (5.2) 5 (3.2) 8 (7.1) 2 (9.5) 0.232
Heart failure 20 (6.9) 5 (3.2) 12 (10.7) 3 (14.3) 0.022
Diabetes mellitus 28 (9.7) 8 (5.1) 13 (11.6) 7 (33.3) <0.001
Hyperlipoidemia 13 (4.5) 6 (3.8) 7 (6.3) 0 (0.0) 0.378
Hematological disease 29 (10) 11 (7.1) 16 (14.3) 2 (9.5) 0.151
Chronic liver disease 41 (14.2) 19 (12.2) 20 (17.9) 2 (9.5) 0.345
Chronic kidney disease 11 (3.8) 4 (2.6) 6 (5.4) 1 (4.8) 0.485
Cerebrovascular disease 11 (3.8) 2 (1.3) 6 (5.4) 3 (14.3) 0.008
Laboratory findings (Mean ±SD)
RBCs (×1012/L) 5.1 ± 1.0 5.3 ± 1.0 a, b 4.8 ± 1.0 4.6 ± 0.9 <0.001
Hemoglobin (g/L) 144.5 ± 29.4 152.8 ± 26.9a, b 135.6 ± 30.5 129.7 ± 20.6 <0.001
Albumin (g/L) 35.5 ± 5.2 39.1 ± 3.3a, b 31.3 ± 3.5 31.1 ± 4.2 <0.001
Creatinine (μmol/L) 65.2 ± 21.4 64.1 ± 14.1 66.4 ± 26.5 71.3 ± 32.7 0.293
BUN (mmol/L) 4.5 ± 1.8 4.4 ± 1.4 4.7 ± 2.2 4.6 ± 1.7 0.549
Total bilirubin (μmol/L) 13.5 (9.3, 18.2) 14.2 (9.7, 18.4) 12.1 (8.9, 18.1) 14.2 (10.4, 20.5) 0.497
CRP (mg/dL) 8.09 (2.7, 30.6) 4.2 (1.7, 14.4)a 18.4 (5.0,55.5) 15.4 (6.2, 77.1) <0.001

Data are presented as the means ± standard deviations (SDs) or n (%). Analysis of variance was applied to continuous variables, and the chi-square test was applied to categorical variables, which was described in the methodology.

a

P < 0.001 compared with NRS-2002 scores 3–4.

b

P < 0.001 compared with NRS-2002 scores ≥ 5.

BMI, body mass index; RBC, red blood cell; BUN, blood urea nitrogen; NRS-2002, Nutrition Risk Screening 2002.