Figure 6.
Box plots (indicating the observed data range of integrated fluorescence intensity (BioTek Synergy H1) after 60 min of incubation at 300 K) for (A) CCL20 (left) and (B) IL-6 (right) concentrations in mouse bronchoalveolar lavage for PBS (white; n = 8) vs. poly-IC in PBS (gray; n = 8). For IL-6 the difference in nanobiosensor fluorescence observed in the group of mice treated with poly-IC vs. the group treated with PBS was statistically significant (**P < 0.01), whereas it was not significant (n.s.) for CCL20 (P = 0.14).The LODs (0.1 femtomoles) for CCL20 and IL-6 are 3.5 and 2.8 integrated fluorescence units, respectively.