Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 18;21:15347354221099537. doi: 10.1177/15347354221099537

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 1. — Chemical structure, Fa values, and combination index of curcumin (Cur) and thymoquinone (TQ) against MCF7. (A) Chemical structure of Cur. (B) Chemical structure of TQ. (C) Fa values of Cur against MCF7. (D) Fa values of TQ against MCF7. (E) Dose-effect curve of Fa 75 of Cur (43.31 µM) and TQ (64.01 µM). (F) Combination index plot of Fa 75 of Cur and TQ. (G) DRI plot of Fa 75 of Cur and TQ. (H) Isobologram plot of Fa 75 of Cur and TQ. (I) Dose-effect curve of Fa 90 of Cur (24.91 µM) and TQ (41.16 µM). (J) Combination index plot of Fa 90 of Cur and TQ. (K) DRI plot of Fa 90 of Cur and TQ. (L) Isobologram plot of Fa 90 of Cur and TQ. The CI values represent the mean of 4 experiments. CI > 1.3: antagonism; CI (1.1-1.3): moderate antagonism; CI (0.9-1.1): additive effect; CI (0.8-0.9): slight synergism; CI (0.6-0.8): moderate synergism; CI (0.4-0.6): synergism; CI (0.2-0.4): strong synergism.