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. 2022 Mar 9;113(5):1808–1820. doi: 10.1111/cas.15304

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© 2022 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Sampling intervals for targeted next generation sequencing (NGS) circulating tumor DNA analysis in patients with metastatic breast cancer. Patients were followed until progressive disease, 24 months, or the cut‐off date (September 30, 2020), whichever comes first. Radiology assessment and tumor markers carcinoembryonic antigen (CEA), cancer antigen (CA) 15‐3 timeline might differ as decided by clinicians. Some figures in Figure 1 were adapted from Servier Medical Art (https://smart.servier.com)