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Circulating tumor DNA (ctDNA) analysis and radiographic images for bone metastasis target lesions. (A). CDK04, (B). CDK07, (C). CDK16, (D). CDK21. RECIST tumor response is shown in colored arrows in the ctDNA profile. CA 15‐3, cancer antigen 15‐3; CEA, carcinoembryonic antigen; CNV, copy number variant; CR, complete response; PD, progressive disease; PR, partial response; SD, stable disease; SNV, single nucleotide variant; VAF, variant allele frequency
