TABLE 1.
Characteristics of patients with a strong family history of pancreatic cancer (N = 18)
| Patient | Pedigree | Age | Sex | Disease | Family history of pancreatic cancer | Past cancer history | Genome sequencing | Outcome |
|---|---|---|---|---|---|---|---|---|
| #1 | #A | 41 | Female | Branch duct–type IPMN | Mother and grandmother | None | – | Alive |
| #2 | #B | 79 | Female | Branch duct–type IPMN | Older brother and younger sister | None | Whole‐exome sequencing | Alive |
| #3 | #B | 82 | Female | Branch duct–type IPMN | Younger brother and younger sister | None | Whole‐exome sequencing | Alive |
| #4 | #C | 52 | Female | Branch duct–type IPMN | Father, younger brother, and father's aunt | None | Gene panel testing | Alive |
| #5 | #D | 73 | Female | Branch duct–type IPMN | Older brother, mother, and mother's uncles | None | Whole‐exome sequencing | Alive |
| #6 | #E | 62 | Female | Branch duct–type IPMN | Father, father's aunt, and grand father | None | – | Alive |
| #7 | #F | 72 | Female | Branch duct–type IPMN | Father, older brother, and younger brother | Breast cancer | Whole‐exome sequencing | Alive |
| #8 | #G | 78 | Female | High‐grade IPMN | Younger sister and daughter | Cervical cancer | Whole genome sequencing | Alive |
| #9 | #G | 51 | Female | High‐grade IPMN | Mother and mother's aunt | None | Whole genome sequencing | Alive |
| #10 | #H | 54 | Female | IPMN‐derived pancreatic cancer | Father and father's grandmother | Breast cancer | – | Dead |
| #11 | #I | 75 | Male | IPMN‐derived pancreatic cancer | Older brothers, father, and mother | None | Whole‐exome sequencing | Alive |
| #12 | #J | 69 | Male | IPMN‐concomitant pancreatic cancer | Older sister and younger sister | Rectal cancer | – | Dead |
| #13 | #K | 72 | Male | IPMN‐concomitant pancreatic cancer | Older brother and younger brother | None | Whole‐exome sequencing | Alive |
| #14 | #L | 79 | Female | IPMN‐derived pancreatic cancer | Mother and older sister | Lung cancer | – | Dead |
| #15 | #M | 82 | Female | IPMN‐concomitant pancreatic cancer | Father and older sister | None | – | Dead |
| #16 | #G | 72 | Female | Non–IPMN‐related pancreatic cancer | Older sister and sister's daughter | None | Whole genome sequencing | Alive |
| #17 | #N | 71 | Male | Non–IPMN‐related pancreatic cancer | Father and father's uncle | Gastric cancer | Whole‐exome sequencing | Alive |
| #18 | #O | 53 | Male | Non–IPMN‐related pancreatic cancer | Father and father's aunt | None | – | Dead |
Abbreviation: IPMN, intraductal papillary mucinous neoplasm.