Table 1.
Baseline demographics
| Demographics | Gradual wean (n = 66) | Rapid wean (n = 73) | p |
|---|---|---|---|
| Age, mean ± SD (yr)a | 55.0 ± 14.3 | 56.8 ± 12.6 | 0.44 |
| Sex, n (%) | 0.85 | ||
|
| |||
| Male | 18 (27) | 18 (25) | |
|
| |||
| Female | 48 (73) | 55 (75) | |
|
| |||
| Race, n (%) | 0.25 | ||
|
| |||
| White | 48 (73) | 57 (78) | |
|
| |||
| Black | 7 (11) | 9 (12) | |
|
| |||
| Asian American | 2 (3) | 3 (4) | |
|
| |||
| Other | 6 (9) | 4 (5) | |
|
| |||
| Unknown | 3 (5) | 0 | |
|
| |||
| Ethnicity, n (%) | 0.59 | ||
|
| |||
| Hispanic | 14 (21) | 12 (16) | |
|
| |||
| Non-Hispanic | 50 (76) | 60 (82) | |
|
| |||
| Unknown | 2 (3) | 1 (1) | |
|
| |||
| Hunt and Hess score, n (%) | 0.16 | ||
|
| |||
| 1 | 6 (9) | 1 (1) | |
|
| |||
| 2 | 13 (20) | 22 (30) | |
|
| |||
| 3 | 29 (44) | 27 (37) | |
|
| |||
| 4 | 12 (18) | 15 (21) | |
|
| |||
| 5 | 6 (9) | 8 (11) | |
|
| |||
| WFNS score, n (%) | 0.24 | ||
|
| |||
| 1 | 16 (24) | 23 (32) | |
|
| |||
| 2 | 24 (36) | 15 (21) | |
|
| |||
| 3 | 2 (3) | 4 (5) | |
|
| |||
| 4 | 17 (26) | 18 (25) | |
|
| |||
| 5 | 7 (11) | 13 (18) | |
|
| |||
| GCS, mean ± SD | 11.4 ± 4.1 | 11.3 ± 4.0 | 0.93 |
| GRAEB, mean ± SD | 3.8 ± 3.1 | 3.7 ± 3.1 | 0.72 |
| Modified GRAEB, mean ± SD | 10.8 ± 8.1 | 9.1 ± 8.0 | 0.20 |
| Treatment, n (%) | 0.42 | ||
|
| |||
| Clipping | 17 (26) | 14 (19) | |
|
| |||
| Coiling | 47 (71) | 54 (74) | |
|
| |||
| Other | 2 (3) | 5 (7) | |
|
| |||
| EVD placement complications, n (%) | 3 (5) | 1 (1) | 0.26 |
| mF, n (%) | 0.42 | ||
|
| |||
| 1 | 5 (8) | 3 (4) | |
|
| |||
| 2 | 7 (11) | 4 (5) | |
|
| |||
| 3 | 28 (42) | 39 (53) | |
|
| |||
| 4 | 26 (39) | 27 (37) | |
|
| |||
| Aneurysm location, n (%) | |||
|
| |||
| ICA | 6 (9) | 8 (11) | 0.71 |
|
| |||
| MCA | 7 (11) | 14 (19) | 0.15 |
|
| |||
| ACA | 5 (8) | 6 (8) | 0.89 |
|
| |||
| Vertebral | 1 (2) | 0 | 0.22 |
|
| |||
| Basilar | 10 (15) | 5 (7) | 0.11 |
|
| |||
| PCA | 2 (3) | 4 (5) | 0.47 |
|
| |||
| Pcomm | 14 (21) | 14 (19) | 0.77 |
|
| |||
| PICA | 6 (9) | 1 (1) | 0.03 |
|
| |||
| AComm | 17 (26) | 20 (27) | 0.83 |
|
| |||
| Other | 1 (2) | 2 (3) | 0.62 |
|
| |||
| Angio negative | 0 | 0 | – |
|
| |||
| Aneurysm size, mean ± SD (mm) | 6.2 ± 3.6 | 6.0 ± 2.7 | 0.67 |
|
| |||
| First wean trial day, mean ± SD | 9.9 ± 5.2 | 8 ± 5.7 | 0.38 |
|
| |||
| Number of weans, median (IQR) | 1 (1–2) | 1 (1–2.5) | 0.007 |
ACA anterior cerebral artery, AComm anterior communicating artery, EVD external ventricular drain, GCS Glasgow coma scale, ICA internal carotid artery, IQR interquartile range, MCA middle cerebral artery, mF modified Fisher scale, PCA posterior cerecral artery, Pcomm posterior communicating artery, PICA posterior inferior cerebellar artery, SD standard deviation, WFNS world federation of neurological surgeons
a
Age range was 19–87 years (min–max). There were three patients aged > 80 years