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. 2022 May 10;13:875691. doi: 10.3389/fimmu.2022.875691

Table 1.

Clinical characteristics of patients left for downstream analysis, classified as recurrent wheezing RSV (RW-RSV), asthma RSV (AS-RSV), and complete recovery RSV cases (CR-RSV).

CR-RSV (n = 28) RW/AS-RSV (n = 40) P-value
Demographic variables
Sex Male 17 (60.07%) 28 (70.0%) 0.447
Age in months (mean [SD])* 7.14 [5.32] 5.85[3.62] <0.001
Ethnicity 0.184
 Western Europe 24 (85.7%) 36 (90.0%)
 Southern Europe 2 (7.1%) 1 (2.5%)
 Southern America 1 (3.6%) 0
 Roma 0 3 (7.5%)
 Other 1 (3.6%) 0
RSV infection 28 (100.0%) 40 (100.0%) 1.000
Past medical history prior to RSV-A
 Premature 4 (14.3%) 4 (10.0%) 0.717
 Atopic Dermatitis* 2 (7.1%) 13 (32.5%) 0.017
 Alimentary allergies 1 (3.6%) 5 (12.5%) 0.399
 Stational allergies 0 2 (5.0%) 0.508
 Asthma 0 0 1.000
Admissions prior to RSV 10 (35.7%) 12 (27.0%) 0.399
Annual bronchitis prior the RSV-A* 3 (10.7%) 21 (52.5%) 0.005
Family history
 Asthma 4 (14.3%) 14 (35.0%) 0.052
 Respiratory problems 5 (17.9%) 15 (37.5%) 0.053
Clinical characteristics of the RSV-H
Respiratory distress 0.147
 Mild 8 (28.6%) 4 (10.0%)
 Moderate 16 (57.1%) 29 (72.5%)
 Severe 4 (14.3%) 7 (17.5%)
Oxygen requirement 23 (82.1%) 25 (62.5%) 0.107
Respiratory support 0.128
 Non-invasive 3 (10.7%) 8 (20%)
 Mechanical 2 (7.1%) 0
Diagnosis 0.093
 Bronchiolitis 25 (89.3%) 31 (77.5%)
 Bronchospasm 0 1 (2.5%)
 Pneumonia 2 (7.1%) 2 (5.0%)
 Other 1 (3.6) 6 (15.0%)
Bacterial superinfection suspected* 20 (71.4%) 12 (30.0%) <0.001
Follow-up 3 years
 Hospital admission 5 (17.9%) 11 (27.5%) 0.962
 Additional episodes of bronchiolitis* 7 (25%) 37 (92.5%) <0.001

Fisher’s exact test is used to assess the association between the different variables. RSV-A, RSV admission; RSV-H, RSV hospitalization.

*Statistically significant variables.