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. 2022 May 10;12:858164. doi: 10.3389/fonc.2022.858164

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Copyright © 2022 Zhang, Tan, Fang, Zhang, Cao and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Contents of PD-1⁺ CD8⁺ T cells, PD-1⁺ CD4⁺ T cells, and PD-1⁺ T_reg cells are related to the efficacy of CCRT. Panel A, Spearman correlation analysis indicates that content of PD-1⁺ CD8⁺ T cells is correlated with efficacy of CCRT; Panel B, Spearman correlation analysis indicates that content of PD-1⁺ CD4⁺ T cells is correlated with efficacy of CCRT; Panel C, Spearman correlation analysis indicates that content of PD-1⁺ Treg cells is correlated with efficacy of CCRT; CR + PR: n = 49; SD + PD: n = 6 ; PD-1, programmed death 1; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; CCRT, concurrent chemoradiotherapy.