Table 2.
Variables | MAFLD | Severe steatosis | Severe fibrosis | ||||||
---|---|---|---|---|---|---|---|---|---|
ORs | 95%CI | P value | ORs | 95%CI | P value | ORs | 95%CI | P value | |
Gender | 1.532 | 0.788, 2.980 | 0.208 | 2.093 | 1.222, 2.583 | 0.007 | 1.195 | 0.597, 2.394 | 0.615 |
Age quartiles | 0.951 | 0.680, 1.329 | 0.767 | 0.983 | 0.748, 1.292 | 0.903 | 0.678 | 0.468, 0.981 | 0.039 |
BMI quartiles | 1.637 | 1.183, 2.266 | 0.003 | 1.824 | 1.405, 2.367 | <0.001 | 1.488 | 1.044, 2.119 | 0.028 |
CRP | 1.203 | 1.065, 2.358 | 0.003 | 1.159 | 1.065, 1.262 | 0.001 | 1.163 | 1.078, 1.254 | <0.001 |
ALT quartiles | 1.417 | 0.924, 2.173 | 0.110 | 1.294 | 0.914, 1.831 | 0.146 | 0.995 | 0.633, 1.565 | 0.984 |
AST quartiles | 0.811 | 0.541, 1.214 | 0.308 | 0.758 | 0.544, 1.055 | 0.101 | 0.906 | 0.596, 1.379 | 0.646 |
γ-GT quartiles | 1.500 | 1.068, 2.107 | 0.019 | 1.342 | 1.018, 1.768 | 0.037 | 1.219 | 0.833, 1.785 | 0.308 |
TC quartiles | 0.807 | 0.537, 1.214 | 0.304 | 0.805 | 0.568, 1.143 | 0.225 | 1.567 | 1.126, 1.986 | 0.044 |
TG quartiles | 1.119 | 0.813, 1.541 | 0.489 | 0.971 | 0.748, 1.261 | 0.825 | 1.582 | 1.128, 2.220 | 0.008 |
HDL-C quartiles | 0.859 | 0.642, 1.147 | 0.303 | 1.006 | 0.794, 1.274 | 0.961 | 1.176 | 0.860, 1.606 | 0.310 |
LDL-C quartiles | 1.305 | 0.902, 1.888 | 0.158 | 1.426 | 1.040, 1.955 | 0.027 | 1.565 | 0.949, 2.582 | 0.080 |
FPG quartiles | 1.025 | 0.752, 1.397 | 0.875 | 0.993 | 0.773, 1.277 | 0.959 | 0.827 | 0.599, 1.142 | 0.250 |
LnFINS quartiles | 0.911 | 0.588, 1.412 | 0.678 | 1.032 | 0.720, 1.479 | 0.863 | 1.406 | 0.891, 2.218 | 0.143 |
LnHOMAIR quartiles | 1.532 | 0.788, 2.980 | 0.208 | 2.093 | 1.222, 2.583 | 0.007 | 1.195 | 0.597, 2.394 | 0.615 |
ORs were determined by univariable logistic regression analysis. Age was plotted in quartiles with value set at < 26, 26-35, 35-54, and ≧54 years old. BMI was plotted in quartiles with levels set at < 29.1, 29.1-33.3, 33.3-38.5, and ≧38.5kg/m2. ALT was plotted in quartiles with levels set at <20.6, 20.6-33.9, 33.9-63.9, and ≧63.9 U/L. AST was plotted in quartiles with levels set at <17.7, 17.7-25.9, 25.9-39.5, and ≧39.5 U/L. γ-GT was plotted in quartiles with levels set at < 23.1, 23.1-35.8, 35.8-55.3, and ≧55.3 U/L. TC was plotted in quartiles with levels set at < 4.04, 4.04-4.61, 4.61-5.30, and ≧5.30 mmol/L. TG was plotted in quartiles with levels set at <1.3, 1.3-1.8, 1.80-2.80, and ≧2.80 mmol/L. HDL-C was plotted in quartiles with levels set at <0.89, 0.89-1.04, 1.04-1.19, and ≧1.19 mmol/L. LDL-C was plotted in quartiles with levels set at <2.1, 2.1-2.7, 2.7-3.4, and ≧3.4 mmol/L. FPG was plotted in quartiles with levels set at <5.6, 5.6-7.0, 7.0-8.2, and ≧8.2 mmol/L. LnFINS was plotted in quartiles with levels set at < 2.5, 2.5-3.1, 3.1-3.6, and ≧3.6 mU/L. LnHOMA-IR was plotted in quartiles with levels set at < 1.4, 1.4-1.9, 1.9-2.4, and ≧2.4. P-values < 0.05 were accepted as statistically significant.