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. 2020 Mar 31;100(6):5712. doi: 10.2340/00015555-3452

Table I.

Characteristics of patients with atopic dermatitis (AD)

Group Samples n Age, years Median (range) Sex% female (n) SCORAD Median (range) Total IgE (IU/ml) Median (range) Asthma % (n) Rhinitis % (n) Asthma and rhinitis % (n)
ELISAa
 Children with AD 60 8 (3–14) 55.0 (33) 37.0 (19.9–47.4) 154.0 (36.50–839.0) 28.3 (17) 35.0 (21) 20.0 (12)
 Adults with AD 67 30(24–42) 52.2(35) 32.0 (16.2–44.5) 198.0 (61.7–802.0) 35.8 (24) 64.2 (43) 35.0 (21)
 Healthy controls 31 39 (28 – 51) 61.3 (19) - 40.0 (8.0–59.0) - - -
Flow cytometryb
Adults with AD 11 29 (21.0–43.0) 27.3 (3) 54.6 (43.6–64.3) 1,458 (357–4352) 18.1 (2) 27.3 (3) 9.1 (1)
 Healthy controls 10 27 (24.0–32.5) 40.0 (4) - - - - -
a

Serum samples of patients with AD analysed for levels of sOX40 and sOX40L by enzyme-linked immunoassay (ELISA).

b

Peripheral blood mononuclear cells from patients with AD analysed for membrane expression of OX40 and OX40L by flow cytometry.

Healthy controls were matched for age and sex to the patients with AD (for the adult group only).

SCORAD: Subjective SCORing Atopic Dermatitis.