Table 2. Uni- and multivariate logistic regression analysis investigating risk factors for de-novo infection within 10 days under antibiotic prophylaxis.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Model 1 | OR (95% CI) | P-value | OR (95% CI) | P-value |
| Age | 1.00 (0.96–1.04) | 0.914 | ||
| Gender, female | 0.40 (0.11–1.53) | 0.182 | ||
| Days on ICU | 0.94 (0.90–0.97) | 0.012 | ||
| Diabetes mellitus | 2.13 (0.77–5.89) | 0.146 | ||
| Previous SBP | 3.92 (1.06–14.48) | 0.041 | ||
| MELD-Score | 0.94 (0.89–0.99) | 0.032 | ||
| ACLF present at bleeding | 7.17 (2.36–21.74) | 0.0005 | 5.52 (1.48–20.61) | 0.011 |
| Concomitant infection at bleeding | 4.99 (1.83–13.6) | 0.002 | ||
| MDRO colonization at baseline | 1.28 (0.49–3.32) | 0.618 | ||
| MDRO colonization during follow-up | 1.42 (0.78–2.58) | 0.256 | ||
Abbreviations: ACLF, acute-on-chronic liver failure; CI, confidence interval; ICU, intensive care; MELD, model for end-stage liver disease; MDRO, multidrug-resistant organism; SBP, spontaneous bacterial peritonitis.