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. 2022 May 24;17(5):e0268638. doi: 10.1371/journal.pone.0268638

Table 4. Uni- and multivariate logistic regression analysis investigating risk factors for death or liver transplantation after one year.

Variables Univariate analysis Multivariate analysis
Model 1 OR (95% CI) P-value OR (95% CI) P-value
Age 0.96 (0.93–1.00) 0.033 0.94 (0.89–0.99) 0.015
ACLF present at bleeding 11.57 (4.43–30.24) <0.0001 9.85 (3.58–27.12) <0.0001
Concomitant infection at bleeding 5.17 (2.11–12.69) 0.003
MDRO colonization at baseline 0.98 (0.42–2.27) 0.958
MDRO colonization during follow-up 0.85 (0.50–1.42) 0.532
Active bleeding at endoscopy 2.52 (1.02–6.23) 0.045
Adequate antibiotic prophylaxis 2.13 (0.86–5.32) 0.102
TIPS insertion 0.19 (0.04–0.94) 0.041
Infection within 10 days 3.78 (1.44–9.94) 0.007
Rebleeding within 10 days 4.45 (1.45–13.66) 0.009 4.59 (1.12–18.83) 0.034

Abbreviations: ACLF, acute-on-chronic liver failure; CI, confidence interval; MELD, model for end-stage liver disease; MDRO, multidrug-resistant organism; TIPS, transjugular intrahepatic portosystemic shunt.