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. 2022 May 24;20(5):e3001637. doi: 10.1371/journal.pbio.3001637

Fig 2. Effects of the SCN lesion and feeding regime on the BW and the size of the litter.

Fig 2

The pregnant rats were either fed AL or exposed to tRF regime. Five groups of female rats were analyzed—sham-operated (SHAM) on AL feeding regime (Group A), SCN-X group on tRF (Group B), SCN-X group on AL (Group C), sham-operated on tRF (Group D), and intact controls on AL (Group E). BW gain during pregnancy was significantly lower in mothers of Group B compared to Group A; however, the number of fetuses per litter was not different between all groups. BW gain of mothers with uterus and fetuses removed was significantly lower for Group B in comparison with Groups A and E, and average BW of fetuses in Group A did not differ to Group B but was slightly lower compared to Group C. Analyzed by Kruskal–Wallis test with Dunn multiple comparisons, * P < 0.05, ** P < 0.01. For raw data, see S1 Data. AL, ad libitum; BW, body weight; SCN, suprachiasmatic nuclei; tRF, time-restricted feeding.