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. 2022 Jan 17;145(4):1410–1421. doi: 10.1093/brain/awac012

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© The Author(s) 2022. Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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DBS programming prediction for an individualized treatment An exhaustive evaluation of this patients on the heat map of cognitive decline detected a preferable electrode contact combination to reduce the risk of cognitive side-effects. We called back this patient and changed stimulation settings from right lead C2 to C3. Parkinsonism was equally controlled (48–52% UPDRS III reduced to baseline) 14 days in the medication OFF state, while the MDRS improved by 7 points to previous DBS settings (still 6 points reduced to preoperative baseline).