Table 1.
Demographic characteristics and chronic stimulation parameters of the independent cohort subdivided in patients with clinically relevant cognitive decline (≥5 points reduction in the 1-year follow-up) and control subjects
| Characteristic | Validation cohort (n = 33) | |
|---|---|---|
| Cognitive decline | Control | |
| n | 6 | 27 |
| Age at surgery, years | 59.2 (±7.1) | 60.7 (±8.0) |
| Disease duration prior to surgery, years | 11.7 (±2.7) | 12.9 (±4.5) |
| Baseline motor severity (UPDRS-III) | 50.2 (±16.9) | 50.0 (±10.8) |
| Baseline side-effect severity (MDRS) | 141.5 (±2.0) | 141.1 (±2.5) |
| Follow-up time, months | 12.0 | 12.0 |
| Motor improvement over baseline, % | 42.8 (±11.3) | 55.5 (±15.9) |
| Follow-up side effect severity (MDRS) | 131.8 (±4.4) | 140.2 (±2.6) |
| Stimulation parameters | ||
| Amplitude, mA | 3.2 (±1.4) | 3.2 (±0.8) |
| Pulse width, µs | 60 | 60 |
| Frequency, Hz | 150.0 (±27.4) | 146.7 (±23.9) |
Values are presented as mean (±SD).