Skip to main content
. Author manuscript; available in PMC: 2022 May 24.
Published in final edited form as: Mol Psychiatry. 2021 Jan 4;26(6):2440–2456. doi: 10.1038/s41380-020-00981-3

Fig. 4.

Fig. 4

VPA increases Wnt/β-catenin signaling and induces LEF1 expression. a Barplot shows percentage of mCherry-positive cells or percentage of mCherry-positive eGFP-positive cells. Data represent mean ± SEM for n=3 cell lines. Statistical analysis: Mann-Whitney U test. Data distribution for 2 experiments for each cell line is shown in Fig. S7. b Scatterplot of logFC from the comparison between NR in vehicle and CTL in vehicle versus NR in VPA and CTL in VPA. Each dot represents a gene. Line indicates a 1:1 relationship. c Expression pattern of key Wnt-signaling genes. P-value from comparison between NR with vehicle and NR treated with VPA. d Top functionally enriched terms from genes identified to be recovered in NR after the addition of VPA. e Channel-related genes that are recovered in NR after treatment with VPA.