Table 3.
Logistic Mixed Model of Factors Associated With In-hospital Mortality in the Matched Data Set
| Deceased | |||
|---|---|---|---|
| Predictors | OR | 95% CI | p Value |
| Max CRP level (mg/L) | 2.06 | 1.69–2.51 | <.001 |
| Min lymphocyte count (G/L) | 0.49 | 0.38–0.63 | <.001 |
| ADL | 0.85 | 0.75–0.95 | <.001 |
| Oxygen saturation < 90% on room air | |||
| No | Ref | Ref | |
| Yes | 2.15 | 1.45–3.17 | <.001 |
| Charlson Comorbidity Index | 1.18 | 1.07–1.29 | .001 |
| Corticosteroid use | .001 | ||
| No | Ref | Ref | |
| Yes | 2.61 | 1.63–4.20 | |
| Age | 1.04 | 1.01–1.07 | .013 |
| qSOFA ≥ 2 | 1.27 | 0.81–2.01 | .295 |
| CFS | |||
| CFS 1–3, fit | Ref | Ref | |
| CFS 4, vulnerable | 1.01 | 0.52–1.98 | .972 |
| CFS 5–9, frail | 1.28 | 0.75–2.18 | .363 |
| GERICOCO cohort | 0.75 | 0.45–1.24 | .267 |
| Random effects | |||
| ICC | 0.11 | ||
| NCenter | 15 | ||
| Observations | 821 | ||
| Marginal R2/conditional R2 | .413/.479 | ||
Notes: 95% CI = 95% confidence interval; ADL = activities of daily living; CRP = C-reactive protein; CFS = Clinical Frailty Score; ICC = intraclass correlation coefficient; OR = odds ratio; qSOFA = quick Sequential Organ Failure Assessment.