Table 2.

Table showing the number and percentage of positive responders to SARS-CoV-2 spike at 1 dose + 10 weeks and 2 doses + 4 weeks measured across three different panels: Oxford Immunotec Panel 1 + 2 and Panel 14 and PITCH total spike. Oxford Immunotec T-SPOT assay defines the cut-off for a positive responder as 6 SFU/250 000 PBMCs, which translates to 24 SFU/10⁶ PBMCs. The PITCH ELISpot assay defines the cut-off for a positive responder as 26 SFU/10⁶ PBMCs. This cut-off is calculated from negative control wells as: (mean + 2 SD). The cohort analyzed here is described in Table 1 (naïve and previously infected groups are combined).

	n	# Responders on Oxford immunotec Panel 1 + 2 (%)	# Responders on Oxford immunotec panel 14 (%)	# Responders on PITCH total spike (%)
Cut-off (SFU/106 PBMCs)	NA	24	24	26
1 dose + 10 weeks	55	30 (55%)	27 (49%)	38 (69%)
2 doses + 4 weeks	99	62 (63%)	68 (69%)	93 (94%)