Table 3.
Studies examining incidence and prevalence of healthcare-associated UTI in diabetic individuals.
| Country [year] | Comorbidity or reason for hospitalization/homecare |
Sample size | % Fa | %DMb | Agec | Measures of associationd | Ref |
|---|---|---|---|---|---|---|---|
| Taiwan [2021] | Diabetic chronic kidney disease | 79,887 | 30.3 | 100 | 59.6 ± 14.0 | IR = 39.8/103 PY | [63] |
| US [2021] | Total knee arthroplasty | 189,327 | NR | NR | NR | OR = 1.34; P < 0.0001 | [109] |
| Thailand [2020] | Ischemic stroke | 370,527 | 46.6 | 20.4 | >65 | OR = 1.34; P < 0.001 | [110] |
| Hemorrhagic stroke | 173,236 | 40.3 | 9.8 | >61 | OR = 1.25; P < 0.099 | ||
| Undetermined stroke | 65,127 | NR | 18.1 | NR | OR = 1.54; P = 0.013 | ||
| US [2019] | Suprapubic catheterization post pelvic organ prolapse surgery |
254 | 100 | 12 | 65.5g | OR = 2.80; P = 0.01 | [111] |
| Taiwan [2019] | Bed-bound elderly on homecare | 598 | 60.5 | 46.5 | 81.9 ± 11.3 | OR = 1.46; P = 0.024 | [112] |
| US [2018] | Traumatic thoracic vertebral fracture repair |
1088 | 31.7 | 50 | 61 | ORcalc = 1.7; P = 0.036 | [113] |
| Canada [2018] | Subarachnoid hemorrhage | 419 | 63.7 | 9.3 | 58 [48–67] | HR = 1.92 | [114] |
| India [2018] | Renal transplant | 210 | NR | NR | NR | 60.71% UTI+ had new- onset post-transplant DM |
[115] |
| Japan [2018] | Cerebral infarction with indwelling urinary catheter |
27,548 | 52 | 23 | 76 ± 12 | OR = 1.43e; P < 0.001 OR = 0.91f; P = 0.24 |
[116] |
| Poland [2018] | Radical cystectomy | 134 | 23 | 19.4 | 65.9 | OR = 3.75; P = 0.026 | [117] |
| Spain [2017] | Total hip/knee arthroplasty | 74,835 | 62.7 | 50 | 71.5 | ORalc = 1.31 | [118] |
| US [2017] | Endoscopic sinus surgery | 644 | 50 | 13.2 | NR | ORalc = 6.78; P =0.03 | [119] |
| Australia [2017] | Anterior cervical discectomy and fusion (ACDF) |
3725 | 49.9 | 11.8 | NR | ORalc = 2.2 | [120] |
| China [2016] | Hospitalized diabetic elderly | 817 | 49.2 | 100 | ≥60 | 3.2% | [121] |
| US [2016] | Radial cystectomy to treat bladder cancer |
3187 | 18.2 | 19.6 | 70 [62–77] | 9.7% developed UTI OR = 0.96; NS |
[122] |
| US [2016] | Radial cystectomy to treat bladder cancer |
1248 | 16.8 | 16.9 | 69 [61–76] | 10% developed UTI OR = 2.27; P < 0.001 |
[123] |
| Taiwan [2015] | Stroke | 221,254 | 39.5 | 4.5 | 64 | OR = 1.66 | [124] |
| Yemen [2015] | Renal transplant-one year follow up | 150 | 38 | 46 | 35.1 | RR = 2.43; P = 0.014 | [125] |
| US [2016] | Head and neck cancer surgery | 31,075 | 58 | 13 | 61.6g | OR = 1.048h; NS | [126] |
| US [2015] | Cardiac surgery, urinary catheter | 4,883 | 33.4 | 31.3 | NR | OR = 2.04; P = 0.013 | [36] |
| US [2014] | Emergency abdominal surgeries | 53,879 | 55.2 | 20.2 | 76.2g | OR = 1.32; P < 0.001 | [127] |
| US [2014] | Total elbow arthroplasty | 3,184 | 67.5 | 15.3 | 59.7 | OR = 2.24; P < 0.001 | [128] |
| US [2014] | Elective lumbar fusion | 15480 | 55.9 | 15.7 | NR | RR = 1.6 − IDDM; P = 0.011 RR = 1.0 − NIDDM; NS |
[129] |
| Sweden [2014] | Ultrasound-guided prostate biopsy | 51,321 | 0 | 8.6 | NR | OR = 1.32 | [130] |
| Turkey [2013] | Hospitalized for various reasons | 930 | 49.8 | 50 | 62.7-DM 54.6-no DM |
ORcalc = 1.4g | [39] |
| Spain [2012] | Solid organ transplant | 4,388 | 33.2 | 18.8 | 50 ± 14.5 | OR = 1.01i; NS OR = 1.02j; P = 0.037 |
[131] |
| China [2011] | Acute ischemic stroke | 12,907 | 38.2 | 27 | 67 [56–75] | ORcalc = 1.61; P < 0.0001 | [132] |
| Sweden [2010] | Radial cystectomy, urinary catheter | 452 | 23 | 88.9 | 30-80 | RR = 2.1 | [133] |
| US [2010] | Non-cardiac surgery | 3112 | 53.8 | 20 | 56.5 ± 16 | ORcalc = 3.28 | [134] |
%Fa refers to percentage of female subjects and %DMb to percentage of diabetic subjects. Agec refers to the average age in years ± standard deviation or [interquartile range] is shown. NR refers to not reported. Measures of associationd: Incidence rate (IR) (shown as IR per 1000 persons per year), hazard ratio (HR), incidence rate ratio (IRR), or odds ratio (OR) for UTI in diabetic individuals is shown. Where available, P values are shown; NS refers to not significant. e,fOdds ratio calculated by multivariate regression for diabetics treated with insuline or notf. g Calculated average age based on the provided information. hOdds ratio adjusted for race and sex was NOT statistically significant (P = 0.697). i,jOdds ratio for UTI in DM versus no DM in the kidney and kidney-pancreas transplant patientsi or in the liver, heart, and lung patientsj.