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. 2022 Feb 10;126(11):1563–1569. doi: 10.1038/s41416-022-01699-5

Table 2.

Univariate and multivariable analysis of baseline clinicopathologic factors for overall survival.

Univariate analysis Multivariable analysis
Factors Hazard ratio (95% C.I) P-value Hazard ratio (95% C.I) P-value
Age <0.001 0.015
 ≤60 1 (reference) 1 (reference)
 >60 1.64 (1.29–2.08) 1.38 (1.07–1.78)
T size <0.001 <0.001
 ≤2 cm 1 (reference) 1 (reference)
 >2 cm 2.38 (1.81–3.13) 1.89 (1.41–2.53)
Nodes <0.001 <0.001
 Negative 1 (reference) 1 (reference)
 Positive 1.95 (1.39–2.29) 1.85 (1.37–2.50)
Grade <0.001 0.002
 I/II 1 (reference) 1 (reference)
 III 1.78 (1.39–2.29) 1.54 (1.18–2.02)
Hormone receptor 0.022 0.022
 Positive 1 (reference) 1 (reference)
 Negative 1.35 (1.04–1.74) 1.39 (1.05–1.84)
CTC <0.001 <0.001
 Positive 1.74 (1.38–2.20) 1.72 (1.34–2.21)
 Negative 1 (reference) 1 (reference)

CI confidence interval, CTC circulating tumour cell.