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. 2022 May 24;12:8562. doi: 10.1038/s41598-022-11999-8

Table 2.

Physical and somatic responses to N, N-DMT.

Coded units and themes Documented in experience, n (%)
All experiences (n = 3778) Experiences with no reported concomitant psychoactive substance use (n = 3242)
Somatic
Somaesthesias 1415 (37.5) 1212 (37.4)
 Body vibration, buzz, or tingling 1026 (27.2) 878 (27.1)
 Body "high" or euphoria 209 (5.5) 174 (5.4)
 Body "load" 180 (4.8) 160 (4.9)
OBE, floating, dissociation, or body dissolving 655 (17.3) 531 (16.4)
Acceleration, falling, or moving at high velocity 332 (8.8) 263 (8.1)
Temperature dysregulation 191 (5.1) 167 (5.2)
 Warmth 151 (4.0) 134 (4.1)
 Cold 40 (1.1) 33 (1.0)
Unpleasant taste 186 (4.9) 167 (5.2)
Pain (body, abdominal, or oropharyngeal) 69 (1.8) 58 (1.8)
Head pressure, headache, or migraine 53 (1.4) 47 (1.4)
Diaphoresis 31 (0.8) 28 (0.9)
Auditory-ringing type sound 583 (15.4) 583 (18.0)
Ringing, buzzing, humming, or vibrating sound 474 (12.5) 406 (12.5)
Static, crackling, "electric", or popping sound 69 (1.8) 58 (1.8)
High pitched tone or tiny tone 40 (1.1) 36 (1.1)
"Neurologic"
Amnestic events 582 (15.4) 582 (17.9)
 Partial amnesia 513 (13.6) 513 (15.8)
 Full amnesia 69 (1.8) 69 (2.1)
 Black out 46 (1.2) 40 (1.2)
 Loss of awareness to being under the influence of DMT 46 (1.2) 36 (1.1)
Motor effects 105 (2.8) 92 (2.8)
 Paralysis 51 (1.3) 44 (1.4)
 Convulsive or athetoid movements, shivering, or shaking 39 (1.0) 34 (1.0)
 Motor incoordination or balance impairment 15 (0.4) 14 (0.4)
Dizziness or light headedness 70 (1.9) 60 (1.9)
Synaesthesia 47 (1.2) 42 (1.3)
Facial or oropharyngeal paraesthesias 18 (0.5) 14 (0.4)
Gastrointestinal
Nausea 107 (2.8) 90 (2.8)
Emesis 69 (1.8) 55 (1.7)
Fecal urgency 8 (0.2) 8 (0.2)
Cardiorespiratory
Tachycardia or dysrhythmia 79 (2.1) 68 (2.1)
Cough or lung harshness 70 (1.9) 60 (1.9)
Dyspnea, tachypnea, or apnea 18 (0.5) 17 (0.5)
Chest pressure or discomfort 17 (0.4) 15 (0.5)
Choking sensation 10 (0.3) 9 (0.3)
Breathing difficulty NOS 69 (1.8) 59 (1.8)
Genitourinary—urinary urgency or incontinence 24 (0.6) 20 (0.6)

DMT dimethyltryptamine, NOS not otherwise specified, OBE out-of-body experience.