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. 2022 May 24;13(5):491. doi: 10.1038/s41419-022-04896-5

Fig. 3. rSmCASP3/7 and rSmCASP6 cleave rSmGSDMEa at two different sites.

Fig. 3

A, B rSmGSDMEa and its mutants (D259A and D262A) were treated with rSmCASP3 or rSmCASP7. The products were analyzed by SDS-PAGE. C rSmGSDMEa was cleaved by rSmCASP6, and the resulting fragment was excised and subjected to Edman sequencing. D rSmGSDMEa and its mutant D202A were treated with rSmCASP6 and then subjected to SDS-PAGE. E A schematic presentation of the SmCASP3/6/7 cleavage sites in SmGSDMEa. For all panels, NT, N-terminal fragment; CT, C-terminal fragment.