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. 2022 Feb 9;126(11):1555–1562. doi: 10.1038/s41416-022-01726-5

Table 3.

Patterns of disease recurrence in patients with oesophageal cancer that achieved R0 resection after 2 vs. 3 courses of neoadjuvant chemotherapy (NAC).

Recurrence site 2 NAC courses (N = 86) 3 NAC courses (N = 82) P value
Overall number of recurrences 25 (29.1%) 20 (26.8%) 0.493
Locoregional 9 (34.6%) 7 (35.0%) 0.978
Distant 16 (61.5%) 13 (65.0%) 0.809
Lymph node 6 (23.1%) 5 (25.0%) 0.880
Liver 4 (15.4%) 1 (5.0%) 0.243
Lung 4 (15.4%) 5 (25.0%) 0.417
Bone 4 (15.4%) 3 (15.0%) 0.971
Brain 0 (%) 1 (5.0%) 0.193
Pleura 2 (7.7%) 0 (0%) 0.125
Others 1 (3.9%) 2 (10.0%) 0.403