Table 2.
Clinical characteristics of various liver diseases in patients without cirrhosis.
| Healthy control | HB | HC | PBC | AIH | |
|---|---|---|---|---|---|
| number | 74 | 9 | 6 | 20 | 31 |
| age (years) | 35.0 ± 8.3 | 44.4 ± 11.6 | 43.7 ± 17.0 | 53.7 ± 10.6 | 57.1 ± 12.2 |
| gender(Female:Male) | 40:34 | 5:4 | 4:2 | 18:2 | 27:4 |
| TB (mg/dL) | 0.8 ± 0.2 | 0.7 ± 0.2 | 0.8 ± 0.3 | 3.0 ± 3.6 | |
| AST (IU) | 42.2 ± 12.4 | 43.2 ± 13.5 | 42.3 ± 21.8 | 350.5 ± 523.3 | |
| ALT (IU) | 60.4 ± 32.0 | 49.8 ± 16.7 | 59.6 ± 77.9 | 459.3 ± 578.4 | |
| LDH (U/L) | 167.3 ± 24.4 | 170.0 ± 32.4 | 192.9 ± 30.8 | 296.2 ± 185.6 | |
| GGT (U/L) | 52.4 ± 73.1 | 56.7 ± 49.1 | 210.2 ± 172.8 | 243.5 ± 248.7 | |
| Albumin (g/dL) | 4.3 ± 0.3 | 4.2 ± 0.4 | 4.1 ± 0.3 | 3.6 ± 0.4 | |
| Platelet (× 104/μL) | 18.4 ± 4.3 | 19.7 ± 5.8 | 23.4 ± 6.3 | 19.8 ± 7.0 | |
| PT(INR) | 1.01 ± 0.05 | 0.99 ± 0.05 | 0.96 ± 0.06 | 1.14 ± 0.17 | |
| M2BPGi | 1.08 ± 0.77 | 1.92 ± 1.82 | 0.94 ± 0.37 | 5.88 ± 4.37 | |
| Type IV collagen (ng/mL) | 133.0 ± 12.1 | 167.0 ± 72.2 | 128.0 ± 52.9 | 264.7 ± 207.4 | |
| Fib4 index | 1.4 ± 0.6 | 1.7 ± 1.3 | 1.5 ± 0.7 | 5.3 ± 4.9 | |
| IgG (mg/dL) | 1597.3 ± 348.4 | 1861.8 ± 558.0 | 1575.3 ± 428.7 | 2639.1 ± 998.0 | |
| IgM (mg/dL) | 128.3 ± 38.8 | 134.8 ± 71.5 | 272.8 ± 178.1 | 235.2 ± 240.0 | |
| AFP (ng/mL) | 3.7 ± 0.6 | 10.9 ± 10.5 | 3.8 ± 2.8 | 39.3 ± 77.3 | |
| GDF15 (pg/dL) | 475.3 ± 145.3 | 519.3 ± 197.5 | 955.7 ± 502.7 | 634.9 ± 247.0 | 1914.0 ± 1327.2 |
HB, hepatitis B; HC, hepatitis C; PBC, primary biliary chorangitis; AIH, autoimmune hepatitis; TB, total bilirubin; AST, asparatate aminotransferase; ALT, alanine aminotransferase; LDH, lactate dehydrogenase; GGT, γ-glutamyl transpeptidase; PT, prothrombin time; INR, international normalized ratio; M2BPGi, Mac-2 binding protein glycosylation isomer; Ig, immunoglobulin; AFP, arfa-fetoprotein; GDF 15, growth differentiated factor 15.