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. 2022 May 11;16:872743. doi: 10.3389/fncel.2022.872743

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Copyright © 2022 Muto, Hamoy, da Silva Ferreira, Hamoy, Lucas, de Mello and Rogez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Electrocorticographic (ECoG) tracing of diazepam (DZP) (A) and extract of Euterpe oleracea stones (EEOS) (B), seizure inhibition after pentylenetetrazol (PTZ) administration. (C) Total power averages of the control records, DZP + PTZ, EEOS + PTZ, and PTZ for PTZ-induced seizure outbreaks. (D) Demonstration of the potency of beta waves after administration of DZP + PTZ and EEOS + PTZ compared to the means obtained from the beta waves for PTZ. Different letters in columns show significant differences after ANOVA followed by Tukey’s test (*p < 0.01, ^***p < 0.0001, n = 9).