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. 2022 May 11;16:872743. doi: 10.3389/fncel.2022.872743

TABLE 1.

Behavioral characterization of seizures triggered by the administration of pentylenetetrazol (PTZ) and after previous administration of diazepam (DZP) or extract of Euterpe oleracea stones (EEOS) (latency in seconds).

Stage Behavior PTZ 60 mg/kg i.p. DZP 5 mg/kg + PTZ i.p. EEOS 300 mg/kg + PTZ i.p.
0 No behavioral changes after PTZ administration.
I The animal has immobility. 43.56 ± 6.560 85.11 ± 6.528
II The animal exhibits rapid vibratory movements and a feathered tail. 58.00 ± 5.760 282 ± 32.06 116.9 ± 12.25
III The animal presents isolated clonic seizures of one or more limbs, especially the anterior limbs. 89.33 ± 6.042 No evolution 170.0 ± 19.10
IV The animal has generalized clonic seizures, abundant salivation, and transient loss of posture reflex. 103.2 ± 5.652 No evolution No evolution
V The animal presents tonic-clonic seizures (Great-mal), loss of posture reflex, and death from respiratory arrest. 165.0 ± 19.70 No evolution No evolution