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. 2022 May 11;13:914039. doi: 10.3389/fpsyt.2022.914039

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Copyright © 2022 Xu, Wang, Chen, Kang, Wang, Zhang, Shu, Liao, Zou, Wei, Ling and Shao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The fALFF results of brain activity in the PAT group. Compared with the HCs, the fALFF of the following regions were increased to various extents: 1-left middle occipital gyrus (t = 4.9), 4-right globus pallidum (t = 4.36), 6-right anterior cingulate and paracingulate gyri (t = 4.24), 9-left lingual gyrus (t = 3.54), and decreased fALFF values in the 2-left inferior parietal gyrus (t = – 4.75), 3-right cerebellum (t = – 4.69), 5-right medial orbitofrontal gyrus (t = – 4.35), 7- left triangle inferior frontal gyrus (t = – 4.05) and 8-left fusiform gyrus (t = – 3.688). The sizes of the spots denote the degree of quantitative changes. HCs, healthy controls; fALFF, fractional amplitude of low-frequency fluctuations; PAT, MGD patient in SO population.