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. 2022 May 11;16:856734. doi: 10.3389/fncel.2022.856734

FIGURE 1.

FIGURE 1

Motor recovery after sciatic nerve crush injury. Motor function recovery of WT and Sort1–/– mice assessed by walking tract analysis and calculation of (A) SFI, (B) stride length, (C,D) step length, (E) step width, and (F) angle of paw placement to the midline, assessed at pre-treatment (time = 0), 3, 7, 9, 11, 18, 25, and 60 days after nerve crush injury. (G) Grip strength was additionally assessed at pre-treatment (time = 0), 3, 9, 11, 18, 25, 31, 38, 45, and 60 days after nerve crush injury. (H) Nerve conduction velocity analysis of sural (sensory; SNCV) and sciatic (motor; MNCV) nerves 60 days after injury on the ipsilateral and contralateral (sham) side. N = 6 WT mice or 6 Sort1–/– mice. Statistical significance was established with multiple measures test (A–G) or two-way ANOVA (H) and Bonferroni’s multiple comparisons post hoc test (*p < 0.05, **p < 0.01, ****p < 0.0001).